Knowledge Area 5 | Antenatal Care
(Aligned with RCOG Core Curriculum 2019)
Antenatal Care is one of the broadest and most clinically integrative areas within obstetrics. According to the current RCOG curriculum framework, antenatal care is not limited to routine visits—it encompasses:
- Pre-pregnancy counselling
- Risk assessment and stratification
- Screening and diagnosis of fetal and maternal conditions
- Surveillance of high-risk pregnancies
- Prevention of adverse outcomes
- Preparation for birth and postnatal transition
It links directly with Maternal Medicine, Fetal Medicine, Infections, Genetics, Public Health, and Obstetric Emergencies.
Foundations of Antenatal Care
- Core Aim: To optimise maternal and fetal outcomes through risk identification, prevention, surveillance, and timely intervention.
- Pregnancy may begin as low risk but evolve into high risk. The clinician must continuously reassess.
Pre-Pregnancy & Pre-Conception Counselling
- Key Components: Optimisation of chronic medical conditions; Medication review (teratogenicity risk); Folic acid (high vs standard dose); BMI optimisation; Smoking and alcohol cessation; Genetic counselling if indicated; Vaccination review
- This overlaps significantly with maternal medicine.
Booking Visit & Initial Risk Assessment
- The booking appointment establishes:
- Maternal Baseline: BMI; Blood pressure; Past obstetric history; Thromboembolism risk; Mental health history; Safeguarding concerns
- Baseline Investigations: FBC; Blood group & antibodies; Hb electrophoresis (if indicated); Infection screening (HIV, HBV, syphilis); Urine culture; Screening for haemoglobinopathies
- This stage determines low-risk vs consultant-led care.
Screening in Pregnancy
- Aneuploidy Screening: Combined screening (11–13+6 weeks); Cell-free DNA testing
- Fetal Anomaly Screening: 20-week anomaly scan; Fetal echocardiography when indicated
- National programme: NHS Fetal Anomaly Screening Programme
Routine Antenatal Care
- Includes structured follow-up visits: BP monitoring; Urine testing; Symphysis–fundal height (low risk); Growth scans (high risk); Fetal movement education; Vaccination (pertussis, influenza)
- Relevant topics: Hyperemesis gravidarum; Vitamin D supplementation; Constipation; Drug prescribing in pregnancy
Social & Cultural Determinants of Health
- Strongly emphasised in curriculum under safeguarding & equality. This is now a high-priority curriculum theme.
- Complex Social Factors: Domestic violence; Substance misuse; Asylum seekers; Teenage pregnancy
- Female Genital Mutilation
- Perinatal Mental Health
Obesity & Advanced Maternal Age
- Increasingly examined.
- Obesity risk stratification; VTE prophylaxis; GDM screening
- Very advanced maternal age risks
High-Risk Pregnancy Surveillance
- Multiple Pregnancy
- Fetal Growth Restriction (FGR): Umbilical artery Doppler; MCA Doppler; Serial growth scans
- Alloimmunisation: Anti-D prophylaxis; Antibody monitoring
- Malpresentation: ECV counselling; Breech management planning
Preterm Birth Prevention
- A major focus area for exam.
- Includes: Cervical length screening; Cerclage; Progesterone; Antenatal corticosteroids; Magnesium sulphate for neuroprotection
Infections in Pregnancy
- Extensive curriculum component.
- Includes: Varicella; CMV; HIV; Malaria; Sepsis; Group B Streptococcus; COVID-19
- Must understand: Screening vs treatment; Vertical transmission; Vaccination safety
Stillbirth & Intrauterine Death
- Focus: Prevention strategies; Care in subsequent pregnancy; Induction protocols
Antepartum Haemorrhage
- These are antenatal diagnoses requiring delivery planning: Placenta previa; Placenta accreta spectrum; Vasa previa
Obstetric Emergencies (Antenatal Context)
- Although overlapping with intrapartum care, antenatal preparation is critical: Maternal collapse; Sepsis; Blood transfusion; Cord prolapse; Shoulder dystocia counselling
- MEOWS chart familiarity is essential.
Genetic Medicine & Fetal Therapy
- Modern curriculum increasingly includes: Chromosomal microarray; Preimplantation genetic testing; Fetal MRI; In-utero surgery (e.g., spina bifida repair)
- Requires understanding of counselling principles.
Final Words
- Do not memorise passively.
- Build algorithmic thinking.
- Practise SBAs & EMQs repeatedly.
- Cross-link with Maternal Medicine and Labour modules.
- Always ask: What is the risk? What is the surveillance? What is the intervention threshold?
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Routine Antenatal Care |
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NICE |
NG201 Antenatal Care 2021 |
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SIP |
#1 Air Travel and Pregnancy 2013 #2 Umbilical Cord Blood Banking #37 Chemical Exposures During Pregnancy 2013 #38 Stem Cell Therapies in Obs & Gynae #43 Vitamin D in Pregnancy #49 Ultrasound from conception to 10+0 wks gestation #50 Developing new pharmaceutical treatments for obstetrics conditions #58 Diagnostic Biomarkers for predicting adverse early pregnancy outcomes |
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TOG |
Vaccination in pregnancy 2015 Constipation in Pregnancy 2015 Vitamin supplementation in pregnancy 2012 Prescription drug use in pregnancy 2012 |
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GTG |
#69 Management of Nausea, Vomiting of Pregnancy and Hyperemesis Gravidarum |
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Non-invasive Prenatal Diagnosis & Screening in Pregnancy Congenital Malformations |
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SIP |
#15 NIPT for chromosomal Abnormality using Maternal Plasma DNA 2014 #60 Combined use of USG and Fetal MRI for comprehensive fetal neurological assessment in Fetal Congenital Cardiac Defects 2019 #64 Clinical Utility of Prenatal Exam Sequencing in the Evaluation of the Fetus with Congenital Anomalies 2021 |
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TOG |
Application of cffDNA testing beyond common aneuploidy 2025 Prenatal genomic testing for ultrasound-detected fetal structural anomalies 2023 Gastrointestinal congenital anomalies requiring surgery 2023 Pitfalls of prenatal diagnosis associate with mosaicism 2023 Diagnosis and management of fetal cardiac arrhythmias 2022 Pre-implantation genetic testing for aneuploidy 2020 Imaging in Pregnancy 2019 Fetal surgery for open spina bifida 2019 Evolution in screening for Down Syndrome Click Here: Summary 2019 Cell-free fetal DNA-based noninvasive prenatal testing of aneuploidy 2017 Prenatal diagnosis in modern era 2016 Preimplantation genetic diagnosis 2016 The use of chromosomal microarray in prenatal diagnosis 2013 Current status of potential organ donation in cases of lethal fetal anomaly 2013 Antenatal and intrapartum care of pregnancy complicated by lethal fetal anomaly 2013 |
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NHS |
Fetal Anomaly Screening Programme Screening in Pregnancy:Website |
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GTG |
#8 Amniocentesis and CVS 2021 |
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CA |
#6 Amniocentesis 2013 |
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Social/ Cultural Factors |
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NICE |
CG110 Pregnancy and Complex Social Factors 2010 |
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TOG |
Opioid misuse in pregnancy 2022 Smoking in Pregnancy 2019 The obstetrics care of asylum seekers and refugee women in UK 2015 Millennium development goal 4: reducing perinatal and neonatal mortality in low-resource settings 2014 |
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Female Genital Mutilation |
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GTG |
#53 Female Genital Mutilation and its Management 2015 |
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TOG |
Tackling female genital mutilation in UK 2017 |
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Domestic Violence |
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NICE |
Domestic violence and abuse |
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TOG |
Domestic Violence: An invisible pandemic 2022 Domestic Violence: a neglected epidemic in Obs & Gynae training 2017 Domestic Violence: a clinical guide for women’s healthcare providers 2012 |
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Perinatal Mental Health |
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NICE |
CG192 Antenatal and Postnatal Mental Health 2020 |
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TOG |
Perinatal mental health: how to ask and how to help 2017 Postpartum psychosis 2013 |
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GP |
#14 Management of women with mental health issues during pregnancy and postnatal period |
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SIGN |
#127 Management of perinatal mood disorders |
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Obesity |
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GTG |
#72 Care of women with Obesity in Pregnancy |
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TOG |
Exercise in Pregnancy 2015 Pregnancy outcome following bariatic surgery 2013 |
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SIP |
#17 Role of Bariatric Surgery in improving reproductive health |
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Preterm Labour |
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GTG |
#73 Care of women presenting with suspected PPROM from 24+0 wks gestation #74 Antenatal Corticosteroids #75 Cervical Cerclage |
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NICE |
NG25 Preterm labour and birth 2022 |
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SIP |
#29 MgSO4 to prevent Cerebral Palsy following Preterm Birth #33 Preterm Labour, Antibiotics and Cerebral Palsy #41 Perinatal Management of pregnant women at threshold of infant viability |
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GPP |
#4 Registration of Stillbirth and Pregnancy Loss before 24 weeks 2005 |
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TOG |
Preventing and reducing morbidity / mortality of preterm birth in singleton pregnancies 2025 The role of antenatal corticosteroids in improving neonatal outcomes 2021 Long-term use of corticosteroids during Pregnancy 2019 Extreme prematurity and perinatal management 2018 Use of MgSO4 for neuroprotection in preterm neonate 2017 Role of transabdominal cervical cerclage techniques in maternity care 2016 |
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Intrauterine Death |
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GTG |
#55 Late IUFD and StillBirth #57 Reduced Fetal Movements |
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TOG |
Care of pregnancies subsequent to stillbirth 2021 Prevention of stillbirth 2015 Use of mifepristone and misoprostol in management of late IUD 2014 |


